GRF 1-44

GRF 1-44 works to stimulate the pituitary gland to produce and release hormones that promote growth. This peptide consists of 44 amino acids. It is a growth hormone releasing factor produced in the arcuate nucleus of the hypothalamus.
GRF 1-44 is released into the pituitary portal circulation where is stimulates gH production and release by the somatotrophs in the gland. GRF 1-44 suspected benefits are enhanced gH production and IGF-1, improved sleep, and improved immunity. The compound affects one of the primary factors of the gH neuroendocrine axis and at the pituitary level through negative feedback and release of somatostatin.